Description

n-(tert-Butoxycarbonyl)-D-Glucosamine is a protected derivative of D-glucosamine, featuring a tert-butoxycarbonyl (Boc) group that serves as a crucial amine-protecting agent in complex organic syntheses. This compound is essential for researchers and manufacturers requiring high-purity, stable intermediates for the development of pharmaceuticals and bioactive molecules. It is primarily utilized in the synthesis of glycosylated compounds, glycopeptides, and other advanced intermediates within the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel glycosylated drugs, antibiotics, and antiviral agents.
• Glycopeptide Synthesis: Used for the controlled introduction of glucosamine moieties in peptide-based drug candidates and research tools.
• Carbohydrate Chemistry Research: Serves as a protected starting material for academic and industrial research into complex oligosaccharides and glycoconjugates.
• Bioconjugation: Employed in the development of antibody-drug conjugates (ADCs) and other targeted therapeutic platforms.
• Fine Chemical Production: Acts as a specialized intermediate for producing high-value chiral compounds and catalysts.
• Biochemical Reagent: Used in enzymatic studies and the preparation of substrates for glycosyltransferase assays.

Basic Information

Product Name	n-(tert-Butoxycarbonyl)-D-Glucosamine
CAS No.	75251-80-8
Molecular Formula	C11H21NO7
Molecular Weight	279.29 g/mol
Synonyms	D-Glucosamine, N-Boc derivative; Boc-D-Glucosamine; N-Boc-D-glucosamine; N-(tert-Butoxycarbonyl)-D-glucosamine; 2-Amino-2-deoxy-D-glucose N-Boc; 1,3,4,5,6-Penta-O-acetyl-2-deoxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]-D-glucopyranose (precursor related); tert-Butyl N-[(2R,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]carbamate
EINECS	Contact for details

Quality Control

Our n-(tert-Butoxycarbonyl)-D-Glucosamine is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and optical rotation analysis, to ensure identity, purity, and chiral integrity. Certificates of Analysis (COA) documenting all critical parameters are available upon request. We adhere to cGMP principles where applicable to support our clients in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Specific range provided on COA
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.