Description

N(Alpha)-Carbamylglucagon is a chemically modified analog of the peptide hormone glucagon, designed for enhanced stability and specific research applications. This compound is critical for biochemical research and pharmaceutical development, particularly in studies related to metabolic regulation and receptor binding. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on diabetes, metabolic disorders, and peptide-based therapeutic discovery.

Application

• Biochemical Research: Used as a stable analog to study glucagon receptor binding, activation mechanisms, and signal transduction pathways.
• Pharmaceutical R&D: Serves as a key intermediate or reference standard in the development of novel peptide therapeutics for metabolic diseases.
• Metabolic Studies: Employed in in vitro and in vivo models to investigate glucose metabolism, glycogenolysis, and related physiological processes.
• Analytical Standard: Used for method development, calibration, and quality control in analytical laboratories using techniques like HPLC and mass spectrometry.
• Enzyme Inhibition Studies: Investigated for its potential to modulate enzymatic activity in metabolic pathways.
• Stability & Formulation Research: Acts as a model compound for studying the stability, delivery, and formulation of peptide-based drugs.

Basic Information

Product Name	N(Alpha)-Carbamylglucagon
CAS No.	75240-87-8
Molecular Formula	C153H225N43O49S
Molecular Weight	3484.7 g/mol
Synonyms	Nα-Carbamylglucagon; Glucagon, Nα-carbamoyl-; N(Alpha)-Carbamoylglucagon; Carbamyl-Glucagon; N-Carbamylglucagon; Glucagon carbamate; 75240-87-8; UNII-9F8Q8K5U4P
EINECS	Contact for details

Quality Control

Our N(Alpha)-Carbamylglucagon is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and tests for related substances and residual solvents. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure full traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture. For short-term use, aliquots may be stored at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in dilute acetic acid or alkaline aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.