Description

n-[(4-Oxoquinazolin-3-Yl)Methyl]Acetamide Dihydrochloride is a high-purity, dihydrochloride salt derivative of a quinazolinone-based compound, offering enhanced stability and solubility for advanced research and development. This chemical serves as a critical pharmaceutical intermediate and a versatile building block in medicinal chemistry for the synthesis of novel therapeutic agents. It is primarily sought by R&D laboratories and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing targeted drug candidates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential kinase inhibitors and other small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Serves as a core scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Reagent: Used in biochemical assays and as a reference standard for analytical method development and validation in quality control laboratories.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value organic molecules for specialized applications.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	n-[(4-Oxoquinazolin-3-Yl)Methyl]Acetamide Dihydrochloride
CAS No.	75159-37-4
Molecular Formula	C12H12N4O2 • 2HCl
Molecular Weight	317.17 g/mol (Free base: 244.25 g/mol)
Synonyms	3-[(Acetylamino)methyl]-4(3H)-quinazolinone dihydrochloride; N-[(4-Oxo-3,4-dihydroquinazolin-3-yl)methyl]acetamide dihydrochloride; Acetamide, N-[(4-oxo-3-quinazolinyl)methyl]-, dihydrochloride; 3-(Acetamidomethyl)quinazolin-4(3H)-one dihydrochloride; Quinazolinone acetamide dihydrochloride
EINECS	Contact for details

Quality Control

Our n-[(4-Oxoquinazolin-3-Yl)Methyl]Acetamide Dihydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.