Description

trans-4-(Trifluoromethyl)Cyclohexanol is a high-purity fluorinated cyclohexanol derivative, a versatile chiral building block prized for its unique structural and electronic properties. Its value lies in introducing the metabolically stable and lipophilic trifluoromethyl group into target molecules, significantly modulating their physicochemical and biological profiles. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, serving as a key intermediate in the synthesis of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for developing novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disease research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the CF₃ group enhances bioactivity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a core component or modifier in the synthesis of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, improving performance and stability.
• Catalyst & Ligand Development: Employed in the design and synthesis of novel chiral catalysts and ligands for asymmetric synthesis.
• Advanced Polymer Chemistry: Acts as a monomer or modifier for creating specialty polymers with enhanced chemical resistance, thermal stability, and unique surface properties.
• Organic Synthesis & Medicinal Chemistry: A versatile building block for constructing complex molecular architectures in academic and industrial R&D laboratories.

Basic Information

Product Name	trans-4-(Trifluoromethyl)Cyclohexanol
CAS No.	75091-93-9
Molecular Formula	C₇H₁₁F₃O
Molecular Weight	168.16 g/mol
Synonyms	trans-4-(Trifluoromethyl)cyclohexan-1-ol; 4-(Trifluoromethyl)cyclohexanol (trans-); (1r,4r)-4-(Trifluoromethyl)cyclohexan-1-ol; (trans)-4-Trifluoromethyl-1-cyclohexanol; 4-(Trifluoromethyl)-1-cyclohexanol, trans-; 75091-93-9; 4-(Trifluoromethyl)cyclohexanol, trans-
EINECS	Contact for details

Quality Control

Our trans-4-(Trifluoromethyl)Cyclohexanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, isomeric composition, and impurity profiles. Custom purity grades and specifications are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% trans-isomer
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.