Description

trans-3-(Trifluoromethyl)Cyclohexanol is a versatile fluorinated cyclohexanol derivative, characterized by its unique stereochemistry and the presence of a trifluoromethyl group, which imparts significant lipophilicity and metabolic stability. This compound is a crucial chiral building block and intermediate in advanced organic synthesis, particularly valued for its ability to modulate the physicochemical properties of target molecules. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty materials sectors for developing novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, especially for central nervous system (CNS) agents and anti-inflammatory drugs.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Acts as a fluorinated component in the synthesis of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs).
• Asymmetric Catalysis: Employed as a ligand or a substrate in stereoselective catalytic reactions to produce enantiomerically pure compounds.
• Flavor & Fragrance Chemistry: Utilized as a precursor for synthesizing novel aroma chemicals with unique olfactory profiles.
• Polymer Modification: Incorporated as a monomer or additive to introduce fluorine into polymers, improving their chemical resistance and surface properties.

Basic Information

Product Name	trans-3-(Trifluoromethyl)Cyclohexanol
CAS No.	75091-91-7
Molecular Formula	C7H11F3O
Molecular Weight	168.16 g/mol
Synonyms	3-(Trifluoromethyl)cyclohexanol, trans-; (1r,3r)-3-(Trifluoromethyl)cyclohexan-1-ol; (trans)-3-(Trifluoromethyl)cyclohexanol; (±)-trans-3-(Trifluoromethyl)cyclohexanol; Cyclohexanol, 3-(trifluoromethyl)-, trans-; 75091-91-7; 3-Trifluoromethyl-cyclohexanol; trans-3-Trifluoromethylcyclohexanol
EINECS	Contact for details

Quality Control

Our trans-3-(Trifluoromethyl)Cyclohexanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by GC or HPLC, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and fluorides. The container should be kept tightly sealed to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (trans-isomer)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.