Description

Cephalosporin C Sodium CAS NO 74970-31-3 is the sodium salt of a naturally occurring β-lactam antibiotic, serving as the fundamental chemical precursor for the synthesis of numerous semi-synthetic cephalosporin antibiotics. Its primary value lies in providing the core 7-aminocephalosporanic acid (7-ACA) nucleus, which is essential for developing advanced generations of antibiotics with improved efficacy and resistance profiles. This high-purity intermediate is critically needed by pharmaceutical manufacturers and research institutions engaged in the development and production of broad-spectrum antibacterial drugs.

Application

• Pharmaceutical Intermediate: As the key starting material for the chemical or enzymatic production of 7-Aminocephalosporanic Acid (7-ACA).
• Antibiotic Synthesis: For the semi-synthetic manufacture of various second, third, and fourth-generation cephalosporin antibiotics (e.g., Cefazolin, Ceftriaxone, Cefepime).
• Biochemical Research: Used in studies of β-lactam biosynthesis, enzyme inhibition, and bacterial resistance mechanisms.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical laboratories.
• Process Development: Employed in R&D for optimizing fermentation, extraction, and purification processes for β-lactam antibiotics.

Basic Information

Product Name	Cephalosporin C Sodium
CAS No.	74970-31-3
Molecular Formula	C16H20N3NaO8S
Molecular Weight	445.40 g/mol
Synonyms	(6R,7R)-7-[(5R)-5-Amino-5-carboxypentanamide]-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate Sodium Salt; Sodium Cephalosporin C; Cephalosporin C Sodium Salt; Antibiotic C 43; Ceph C Sodium; 7-(5-Amino-5-carboxyvaleramido)cephalosporanic Acid Sodium Salt
EINECS	Contact for details

Quality Control

Our Cephalosporin C Sodium is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and assay, IR for identification, and tests for related substances and residual solvents, ensuring it meets stringent standards suitable for pharmaceutical synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
pH (10% solution)	5.0 - 7.0
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.