Description

4-Nitrobenzoate Trifluoro Methanol is a specialized fluorinated organic intermediate of significant interest in advanced chemical synthesis. This compound matters for its unique trifluoromethyl and nitro-substituted benzoate structure, which imparts valuable electronic and steric properties to target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in the development of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring trifluoromethyl groups for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the nitro and trifluoromethyl functionalities contribute to biological activity.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing groups.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and as a fluorinated synthon for introducing the -CF3 moiety into complex organic frameworks in medicinal chemistry.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Product Name	4-Nitrobenzoate Trifluoro Methanol
CAS No.	74953-35-8
Molecular Formula	C9H6F3NO4
Molecular Weight	249.14 g/mol
Synonyms	4-Nitrobenzoyl Trifluoromethanol; Trifluoromethyl 4-Nitrobenzoate; (4-Nitrobenzoyloxy)trifluoromethane; 4-Nitrobenzoic Acid Trifluoromethyl Ester; α,α,α-Trifluoro-4-nitrobenzyl Alcohol; p-Nitrobenzotrifluoromethanol; 4-Nitro-α,α,α-trifluorotoluene Benzoate
EINECS	Contact for details

Quality Control

Our 4-Nitrobenzoate Trifluoro Methanol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to verify identity and purity against established specifications. Certificates of Analysis (COA) detailing all test results are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.