Description

[[(S)-1-Phenylethyl](Phenylmethyl)Amino]Diphenylphosphine CAS NO 74952-81-1 is a chiral, P,N-bidentate ligand widely used in asymmetric catalysis. Its value lies in its ability to induce high enantioselectivity in transition metal-catalyzed reactions, which is critical for producing optically pure intermediates. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control in their synthetic processes.

Application

• As a chiral ligand for asymmetric hydrogenation of olefins, ketones, and imines.
• In asymmetric cross-coupling reactions (e.g., Suzuki-Miyaura, Heck) to construct chiral carbon centers.
• For enantioselective allylic substitution reactions in complex molecule synthesis.
• As a key component in catalyst systems for the production of pharmaceutical intermediates and active pharmaceutical ingredients (APIs).
• In the synthesis of agrochemicals and flavors & fragrances requiring specific stereochemistry.
• For academic and industrial R&D in homogeneous catalysis and new methodology development.

Basic Information

Item	Details
Product Name	[[(S)-1-Phenylethyl](Phenylmethyl)Amino]Diphenylphosphine
CAS No.	74952-81-1
Molecular Formula	C27H26NP
Molecular Weight	395.48 g/mol
Synonyms	(S)-[(R)-1-Phenylethyl](phenylmethyl)amino]diphenylphosphine; (S)-N-Benzyl-1-phenylethylaminodiphenylphosphine; (S)-BPA-P; (S)-Benzyl(1-phenylethyl)aminodiphenylphosphine; P,N-Ligand BPA-P (S form); Chiral P,N-Bidentate Ligand; (S)-N-Benzyl-α-phenylethylaminodiphenylphosphine
EINECS	Contact for details

Quality Control

Our [[(S)-1-Phenylethyl](Phenylmethyl)Amino]Diphenylphosphine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for sensitive catalytic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is easily oxidized and moisture-sensitive; allow the container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.