Description

Pregnane-3,17,20-Triol-3-Glucuronide is a high-purity steroid glucuronide conjugate, a crucial metabolite and reference standard in biochemical research and pharmaceutical development. This compound is essential for analytical method development, calibration, and quality control in studies related to steroid metabolism and hormone profiling. It serves as a critical material for researchers and quality control laboratories in the pharmaceutical, clinical diagnostics, and life science sectors requiring precise and reliable reference materials.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quantification and identification of steroid metabolites in drug development and bioanalytical studies.
• Clinical Diagnostics: Serves as a calibrator or control in mass spectrometry (MS) and high-performance liquid chromatography (HPLC) assays for detecting hormonal disorders and metabolic conditions.
• Biochemical Research: Employed in enzymatic studies to investigate glucuronidation pathways, steroid hormone metabolism, and the function of UDP-glucuronosyltransferase (UGT) enzymes.
• Metabolite Identification: A key standard in ADME (Absorption, Distribution, Metabolism, and Excretion) studies for characterizing the metabolic fate of pregnane-derived pharmaceuticals.
• Forensic Toxicology: Utilized as an analytical standard in confirmatory testing for endogenous steroids and their metabolites.

Basic Information

Product Name	Pregnane-3,17,20-Triol-3-Glucuronide
CAS No.	74915-85-8
Molecular Formula	C27H44O10
Molecular Weight	528.64 g/mol
Synonyms	3α,17α,20α-Trihydroxy-5β-pregnan-3-yl-β-D-glucopyranosiduronic Acid; 5β-Pregnane-3α,17α,20α-triol 3-Glucuronide; Pregnanetriol Glucuronide; 3-Glucuronosido-5β-pregnane-3α,17α,20α-triol; PTG; Pregnane-3α,17α,20α-triol-3-yl-β-D-glucuronide; 5β-Pregnan-3α,17α,20α-triol 3-yl-β-D-Glucopyranosiduronic Acid
EINECS	Contact for details

Quality Control

Our Pregnane-3,17,20-Triol-3-Glucuronide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and reference applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and trace moisture content is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.