Description

Glucagon (1-37) (Porcine) is a synthetic peptide fragment of the full-length porcine glucagon hormone, specifically encompassing the first 37 amino acids. This high-purity peptide is critical for biochemical research and pharmaceutical development, particularly in studies of glucose metabolism and receptor binding. It serves as an essential reference standard and active pharmaceutical ingredient (API) intermediate for researchers and manufacturers in the life sciences and biotechnology sectors.

Application

• Biochemical Research: Used as a reference standard and tool compound for studying glucagon receptor (GCGR) activation, signaling pathways, and structure-activity relationships (SAR).
• Pharmaceutical Development: Serves as a key intermediate or starting material in the synthesis of glucagon analogs and related peptide therapeutics.
• Metabolic Studies: Employed in in vitro and ex vivo experiments to investigate its hyperglycemic effects, liver glycogenolysis, and role in glucose homeostasis.
• Quality Control: Acts as a certified reference material (CRM) for the analytical testing and validation of glucagon-related products in QC laboratories.
• Antibody Production: Utilized as an immunogen for generating specific polyclonal or monoclonal antibodies against glucagon for diagnostic assays.

Basic Information

Product Name	Glucagon (1-37) (Porcine)
CAS No.	74870-06-7
Molecular Formula	C₁₅₃H₂₂₅N₄₃O₄₉S
Molecular Weight	3482.7 g/mol
Synonyms	Porcine Glucagon (1-37); Glucagon 1-37, porcine; Glucagon Fragment 1-37 (Porcine); H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH (porcine sequence); UNII-9V3F5668AM; Glucagon (swine); Pancreatic glucagon (1-37), porcine
EINECS	Contact for details

Quality Control

Our Glucagon (1-37) (Porcine) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and tests for related substances and residual solvents, ensuring it meets high-grade standards suitable for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Amino Acid Analysis	± 10% of theoretical
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Bacterial Endotoxins	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.