Description

2-(4-Bromophenyl)Acetamide is a versatile brominated aromatic amide building block, essential for advanced organic synthesis and pharmaceutical research. Its value lies in its role as a key intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This high-purity compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the bromophenyl moiety.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers where bromine acts a site for further functionalization via cross-coupling reactions.
• Chemical Biology Probes: Utilized as a building block for developing molecular probes and tags used in biochemical and cellular studies.
• Custom Synthesis and Contract Manufacturing: A key raw material for custom synthesis organizations (CSOs) and CDMOs serving the global life sciences market.

Basic Information

Product Name	2-(4-Bromophenyl)Acetamide
CAS No.	74860-13-2
Molecular Formula	C8H8BrNO
Molecular Weight	214.06 g/mol
Synonyms	p-Bromophenacetamide; 4'-Bromoacetophenone amide; (4-Bromophenyl)acetamide; 2-(4-Bromophenyl)ethanamide; 4-Bromo-α-toluamide; NSC 403697; 1-(4-Bromophenyl)-2-amino-2-oxoethane; Acetamide, N-(4-bromophenyl)-
EINECS	Contact for details

Quality Control

Our 2-(4-Bromophenyl)Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.