Description

(2R,3R)-(+)-Bis(Diphenylphosphino)Butane is a high-purity, chiral bidentate phosphine ligand essential for asymmetric catalysis. Its precise stereochemistry enables the production of enantiomerically pure compounds, which is critical for pharmaceutical and fine chemical synthesis. This ligand is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries for developing novel chiral catalysts and processes.

Application

• As a key chiral ligand in asymmetric hydrogenation reactions for pharmaceutical intermediates.
• Catalyst component in the synthesis of enantiomerically pure agrochemicals and flavors/fragrances.
• Used in cross-coupling reactions (e.g., Suzuki, Heck) to control stereoselectivity.
• Essential for academic and industrial R&D in developing new catalytic systems.
• Precursor for the preparation of transition metal complexes with specific chiral environments.
• Employed in the synthesis of specialty polymers and advanced materials requiring chiral induction.

Basic Information

Product Name	(2R,3R)-(+)-Bis(Diphenylphosphino)Butane
CAS No.	74839-84-2
Molecular Formula	C28H28P2
Molecular Weight	426.47 g/mol
Synonyms	(R,R)-DIPAMP; (2R,3R)-(-)-1,2-Bis[(2-methoxyphenyl)phenylphosphino]ethane (common mis-assignment); (R,R)-1,2-Bis(diphenylphosphino)butane; (+)-DIPAMP; (R,R)-DIPAMP ligand; (2R,3R)-DIPAMP; (R,R)-1,2-Bis(o-anisylphenylphosphino)ethane (related compound); Chiraphos derivative
EINECS	Contact for details

Quality Control

Our (2R,3R)-(+)-Bis(Diphenylphosphino)Butane undergoes rigorous quality testing to ensure compliance with industry standards for chiral purity and chemical integrity. Certificates of Analysis (COA) are available upon request, detailing parameters such as enantiomeric excess, chemical purity, and identity confirmation.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and maintain stability. Keep the container in a cool, dry, and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.