Description

Ac-Arg-Oet Hcl CAS NO 74802-30-5 is a protected arginine derivative, specifically the ethyl ester of N-acetyl-L-arginine hydrochloride. This compound serves as a crucial building block in peptide synthesis and pharmaceutical research, offering a protected guanidino group for controlled chemical manipulation. It is primarily utilized by research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in the production of bioactive peptides and novel therapeutic agents.

Application

• Peptide Synthesis Intermediate: A key protected amino acid derivative for solid-phase and solution-phase peptide synthesis.
• Pharmaceutical Research: Used in the development and scale-up of peptide-based active pharmaceutical ingredients (APIs).
• Biochemical Tool: Employed in studies of enzyme-substrate interactions, particularly those involving arginine-rich sequences.
• Protecting Group Strategy: The acetyl and ethyl ester groups provide orthogonal protection for the α-amino and carboxyl functions of arginine.
• Reference Standard: Serves as a high-purity analytical standard for quality control in peptide manufacturing.

Basic Information

Product Name	Ac-Arg-Oet Hcl
CAS No.	74802-30-5
Molecular Formula	C10H21N5O3 • HCl
Molecular Weight	295.77 g/mol
Synonyms	N-Acetyl-L-arginine ethyl ester hydrochloride; Ac-L-Arg-OEt • HCl; Nα-Acetyl-Nω-[(aminoiminomethyl)amino]-L-norvaline ethyl ester hydrochloride; L-Norvaline, N2-acetyl-N5-(aminoiminomethyl)-, ethyl ester, hydrochloride; Ethyl N2-acetyl-N5-carbamimidoyl-L-ornithinate hydrochloride
EINECS	Contact for details

Quality Control

Our Ac-Arg-Oet Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) documenting purity, assay, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation	[α]D20: Contact for details
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.