Description

[2-[Bis(2,4,6-Trimethylphenyl)Methyl]-4,6-Dimethylphenyl]Dimethylphosphine is a sterically hindered, electron-rich phosphine ligand, a key building block in advanced organometallic chemistry. Its primary value lies in its ability to stabilize reactive metal centers and modulate catalytic activity in cross-coupling and other transition metal-catalyzed reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-performance, tailor-made catalysts for complex synthesis.

Application

• Catalyst Ligand for Cross-Coupling Reactions: A crucial component in Buchwald-Hartwig amination, Suzuki-Miyaura, and Negishi couplings for C-C and C-N bond formation.
• Pharmaceutical Intermediate Synthesis: Used in the development and scalable production of active pharmaceutical ingredients (APIs) requiring sophisticated catalytic systems.
• Agrochemical Research & Development: Employed in the synthesis of novel, complex molecules for crop protection and plant science applications.
• Polymerization Catalyst Systems: Serves as a ligand in olefin polymerization and other coordination-insertion polymerization catalysts.
• Material Science & OLED Development: Used in the synthesis of organometallic complexes for electronic materials, including light-emitting diodes (OLEDs).
• Academic & Industrial R&D: A valuable reagent for exploring new catalytic methodologies and reaction mechanisms in both academic and corporate research laboratories.

Basic Information

Product Name	[2-[Bis(2,4,6-Trimethylphenyl)Methyl]-4,6-Dimethylphenyl]Dimethylphosphine
CAS No.	74793-19-4
Molecular Formula	C31H41P
Molecular Weight	444.63 g/mol
Synonyms	Dimethyl[2-[bis(2,4,6-trimethylphenyl)methyl]-4,6-dimethylphenyl]phosphine; DTMPP; (2,4,6-Trimethylphenyl)bis(2,4,6-trimethylbenzyl)phosphine (common representation); JohnPhos-type ligand derivative; Sterically hindered triarylphosphine ligand; Tris(2,4,6-trimethylphenyl)phosphine analog; Electron-rich phosphine; Buchwald ligand precursor
EINECS	Contact for details

Quality Control

Our [2-[Bis(2,4,6-Trimethylphenyl)Methyl]-4,6-Dimethylphenyl]Dimethylphosphine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C, 31P) and HPLC analysis, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee batch-to-batch consistency and support your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its sensitivity to oxidation, this material should be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature in a dry environment before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.