Description

Dicyclohexyl[2(Or 5)-Methyl-5(Or 2)-(1-Methylethyl)Cyclohexyl]Phosphine is a specialized organophosphorus ligand of significant interest in advanced catalytic chemistry. Its value lies in its ability to modulate the activity and selectivity of transition metal catalysts, particularly in asymmetric synthesis and cross-coupling reactions. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel synthetic pathways and optimize manufacturing processes.

Application

• Asymmetric Catalysis: A key ligand for rhodium, iridium, and palladium complexes in enantioselective hydrogenation and C-C bond-forming reactions.
• Pharmaceutical Intermediates: Enables the synthesis of chiral active pharmaceutical ingredients (APIs) with high optical purity.
• Agrochemical Synthesis: Used in the production of advanced, stereochemically defined pesticides and herbicides.
• Cross-Coupling Reactions: Facilitates Suzuki, Heck, and Negishi couplings for constructing complex biaryl and olefin structures.
• Fine Chemical Manufacturing: Critical for producing high-value specialty chemicals, flavors, and fragrances.
• Academic & Industrial R&D: A valuable tool for developing new catalytic methodologies and exploring novel reaction spaces.
• Homogeneous Catalysis: Improves catalyst lifetime and turnover number (TON) in homogeneous catalytic systems.

Basic Information

Product Name	Dicyclohexyl[2(Or 5)-Methyl-5(Or 2)-(1-Methylethyl)Cyclohexyl]Phosphine
CAS No.	74764-13-9
Molecular Formula	C22H41P
Molecular Weight	336.54 g/mol
Synonyms	Dicyclohexyl(2-methyl-5-propan-2-ylcyclohexyl)phosphane; Dicyclohexyl(2-methyl-5-isopropylcyclohexyl)phosphine; (2-Methyl-5-isopropylcyclohexyl)dicyclohexylphosphine; Tertiary Phosphine Ligand 74764-13-9; Asymmetric Synthesis Ligand; Bulky Phosphine Ligand; Chiral Phosphine; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of Dicyclohexyl[2(Or 5)-Methyl-5(Or 2)-(1-Methylethyl)Cyclohexyl]Phosphine adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive catalytic applications. All materials undergo rigorous analytical testing, including NMR, HPLC, and elemental analysis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This compound is easily oxidized and moisture-sensitive; prolonged exposure to air should be avoided.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.