Description

5-Amino-2-Hexenedioic Acid is a versatile bifunctional organic compound containing both an amino and two carboxylic acid groups, making it a valuable chiral building block for chemical synthesis. Its unique structure allows it to serve as a key intermediate in the production of complex molecules, particularly in the pharmaceutical and fine chemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), peptide mimetics, and specialty polymers who require high-purity, reliable synthetic intermediates.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, especially in oncology and neurology research.
• Peptide & Amino Acid Derivative Synthesis: Used to create non-natural amino acids and modify peptide backbones to enhance stability and bioactivity.
• Ligand & Catalyst Development: Serves as a precursor for chelating ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer & Material Science: A monomer for producing functionalized polyamides and polyesters with specific thermal or mechanical properties.
• Agrochemical Research: Employed in the development of new herbicides and plant growth regulators.
• Bioconjugation & Diagnostic Reagents: Utilized to create linkers and probes for antibody-drug conjugates (ADCs) and diagnostic assays.

Basic Information

Product Name	5-Amino-2-Hexenedioic Acid
CAS No.	74743-93-4
Molecular Formula	C6H9NO4
Molecular Weight	159.14 g/mol
Synonyms	5-Amino-2-hexenedioic acid; (E)-5-Aminohex-2-enedioic acid; 2-Hexenedioic acid, 5-amino-; 5-Amino-2-hexene-1,6-dioic acid; Glutaconic acid, 5-amino-; 5-Aminoglutaconic acid; (2E)-5-Amino-2-hexenedioic acid
EINECS	Contact for details

Quality Control

Our 5-Amino-2-Hexenedioic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.