Description

1-Acetyl-4-[2-(Trifluoromethyl)Phenyl]-1H-Pyrrole-3-Carbonitrile is a high-value, multi-functional heterocyclic building block characterized by its pyrrole core and trifluoromethylphenyl substituent. This compound is essential for research and development in advanced organic synthesis, where its unique structure enables the creation of novel molecular architectures. It is primarily sought after by pharmaceutical and agrochemical R&D teams for the development of new active ingredients, as well as by material scientists exploring specialty polymers and electronic materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Active Ingredient R&D: Serves as a core structure for developing novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Organic Light-Emitting Diode (OLED) Materials: Used in the synthesis of advanced electron-transport or host materials for display and lighting technologies.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create specialized ligands for catalytic processes.
• Fluorescent Probe and Dye Synthesis: Acts as a precursor for developing sensitive chemical sensors and imaging agents.
• Academic and Industrial Research: A versatile building block for methodological studies in heterocyclic and fluorine chemistry.

Basic Information

Product Name	1-Acetyl-4-[2-(Trifluoromethyl)Phenyl]-1H-Pyrrole-3-Carbonitrile
CAS No.	74738-12-8
Molecular Formula	C14H9F3N2O
Molecular Weight	278.23 g/mol
Synonyms	1-Acetyl-4-(2-(trifluoromethyl)phenyl)-1H-pyrrole-3-carbonitrile; 4-(2-Trifluoromethylphenyl)-1-acetyl-1H-pyrrole-3-carbonitrile; 1H-Pyrrole-3-carbonitrile, 1-acetyl-4-[2-(trifluoromethyl)phenyl]-; 1-Acetyl-4-(α,α,α-trifluoro-o-tolyl)-1H-pyrrole-3-carbonitrile; 74738-12-8; 1-Acetyl-4-(2-trifluoromethylphenyl)pyrrole-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 1-Acetyl-4-[2-(Trifluoromethyl)Phenyl]-1H-Pyrrole-3-Carbonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request. We adhere to cGMP principles where applicable to support our clients' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.