Description

tert-Butyl(Cyclohexyl)(Methyl)Phosphine is a specialized tertiary phosphine ligand, a key building block in advanced organometallic chemistry and catalysis. Its sterically demanding and electron-rich structure makes it a highly effective ligand for facilitating challenging cross-coupling and hydrogenation reactions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise control over metal-catalyzed transformations to synthesize complex molecules.

Application

• As a ligand in homogeneous catalysis for cross-coupling reactions (e.g., Suzuki-Miyaura, Buchwald-Hartwig amination).
• Utilized in asymmetric hydrogenation processes to create chiral intermediates for active pharmaceutical ingredients (APIs).
• Employed in olefin polymerization catalysis and other organometallic transformations.
• Serves as a precursor for synthesizing more complex phosphine ligands and metal complexes.
• Applied in academic and industrial R&D for developing new catalytic methodologies.
• Used in the manufacture of specialty chemicals and high-value fine chemicals.

Basic Information

Product Name	tert-Butyl(Cyclohexyl)(Methyl)Phosphine
CAS No.	74685-81-7
Molecular Formula	C11H23P
Molecular Weight	186.28 g/mol
Synonyms	tert-Butyl(cyclohexyl)(methyl)phosphane; (tert-Butyl)(cyclohexyl)(methyl)phosphine; Methyl(tert-butyl)cyclohexylphosphine; t-BuCyMePhos; Phosphine, tert-butylcyclohexylmethyl-; tert-Butyl-methyl-cyclohexyl-phosphine
EINECS	Contact for details

Quality Control

Our tert-Butyl(Cyclohexyl)(Methyl)Phosphine is produced and handled under strict quality protocols to ensure batch-to-batch consistency and high purity, critical for sensitive catalytic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality management system adheres to cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. This product is easily oxidized and must be stored under an inert atmosphere (argon or nitrogen). Recommended storage temperature is 2-8°C to maintain stability. Handle and open containers only in a controlled, moisture-free environment to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC or NMR)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.