Description

2,3-Dimethoxy-5-[(Methylamino)Sulphonyl]-n-[(1-Methyl-2-Pyrrolidinyl)Methyl]Benzamide Monohydrochloride is a high-purity, complex organic salt with significant pharmacological research interest. This compound matters as a key advanced pharmaceutical intermediate or reference standard in the development of novel therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories and contract research organizations (CROs) engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate or building block in the synthesis of potential new chemical entities (NCEs) for central nervous system (CNS) or other therapeutic targets.
• Medicinal Chemistry Studies: Used as a reference compound for structure-activity relationship (SAR) studies to optimize drug potency, selectivity, and pharmacokinetic properties.
• Analytical Standard: Employed as a high-purity standard for method development and validation in analytical laboratories using HPLC, LC-MS, or NMR.
• Preclinical Investigation: Utilized in in vitro and in vivo studies to evaluate biological activity, mechanism of action, and toxicity profiles.
• Process Chemistry Development: Acts as a key material for scaling up synthetic routes and optimizing manufacturing processes under Good Manufacturing Practice (GMP) guidelines.
• Academic Research: Supports university and institutional research projects focused on organic synthesis, pharmacology, and neurochemistry.

Basic Information

Product Name	2,3-Dimethoxy-5-[(Methylamino)Sulphonyl]-n-[(1-Methyl-2-Pyrrolidinyl)Methyl]Benzamide Monohydrochloride
CAS No.	74651-67-5
Molecular Formula	C17H28N4O5S • HCl
Molecular Weight	445.95 g/mol
Synonyms	5-(Methylaminosulfonyl)-2,3-dimethoxy-N-[(1-methyl-2-pyrrolidinyl)methyl]benzamide hydrochloride; 2,3-Dimethoxy-5-[(methylamino)sulfonyl]-N-[(1-methyl-2-pyrrolidinyl)methyl]benzamide hydrochloride; Benzamide, 2,3-dimethoxy-5-[(methylamino)sulfonyl]-N-[(1-methyl-2-pyrrolidinyl)methyl]-, monohydrochloride; 74651-67-5 (CAS); 5-(N-Methylsulfamoyl)-2,3-dimethoxy-N-[(1-methylpyrrolidin-2-yl)methyl]benzamide hydrochloride
EINECS	Contact for details

Quality Control

Our 2,3-Dimethoxy-5-[(Methylamino)Sulphonyl]-n-[(1-Methyl-2-Pyrrolidinyl)Methyl]Benzamide Monohydrochloride is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC for assay and purity, NMR and IR for structural confirmation, and KF titration for moisture content. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Purity (HPLC)	≥97.0% (Total impurities ≤3.0%)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.