Description

3-Azabicyclo[3.1.0]Hexane-2-Carbonitrile, 3-Acetyl- (9Ci) is a high-value, bicyclic nitrile building block with a constrained, fused-ring structure. This compound is critical for medicinal chemistry research and the synthesis of complex, biologically active molecules, particularly in the development of new pharmaceuticals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor for the development of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral drug discovery programs.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing conformationally restricted analogs in structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Agrochemical Synthesis: Employed in the research and development of new herbicides and insecticides, leveraging its unique bicyclic framework.
• Fine Chemical Production: Acts as a specialized building block for synthesizing complex molecules used in advanced materials and specialty chemicals.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	3-Azabicyclo[3.1.0]Hexane-2-Carbonitrile, 3-Acetyl- (9Ci)
CAS No.	74650-13-8
Molecular Formula	C8H10N2O
Molecular Weight	150.18 g/mol
Synonyms	3-Acetyl-3-azabicyclo[3.1.0]hexane-2-carbonitrile; 2-Cyano-3-acetyl-3-azabicyclo[3.1.0]hexane; 3-Azabicyclo[3.1.0]hexane-2-carbonitrile, 3-acetyl-; 74650-13-8; 3-Acetyl-3-azabicyclo[3.1.0]hexan-2-carbonitrile
EINECS	Contact for details

Quality Control

Our 3-Azabicyclo[3.1.0]Hexane-2-Carbonitrile, 3-Acetyl- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data, including HPLC/GC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) is supplied with each batch to guarantee compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.