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Chloro(Cyclohexyl)[1,7,7-Trimethylbicyclo[2.2.1]Heptan-2-Yl]Phosphine CAS NO 74630-28-7
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CAS No.:74630-28-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Chloro(Cyclohexyl)[1,7,7-Trimethylbicyclo[2.2.1]heptan-2-yl]phosphine is a specialized organophosphorus compound featuring a unique sterically hindered structure derived from camphor and cyclohexane. This compound matters as a highly effective ligand in transition metal catalysis, offering significant advantages in controlling reaction selectivity and enhancing catalyst stability. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel synthetic routes and catalytic processes.
Application
- Catalytic Ligand in Cross-Coupling Reactions: Used as a sophisticated phosphine ligand in palladium-catalyzed Suzuki, Heck, and Negishi couplings for constructing complex carbon-carbon bonds in API intermediates.
- Asymmetric Synthesis: Employed in the development of chiral catalysts for enantioselective hydrogenation and hydroformylation reactions critical for producing single-isomer pharmaceuticals.
- Polymerization Catalyst Component: Serves as a ligand in olefin polymerization and metathesis catalysts for creating specialty polymers with tailored properties.
- Agrochemical Intermediate Synthesis: Facilitates key synthetic steps in the production of advanced, high-performance crop protection agents.
- Material Science Research: Utilized in the synthesis of novel organometallic complexes and metal-organic frameworks (MOFs) for catalytic and sensing applications.
- Process Development & Scale-Up: Provides a robust ligand option for chemists optimizing catalytic processes from laboratory to pilot plant scale.
Basic Information
| Product Name | Chloro(Cyclohexyl)[1,7,7-Trimethylbicyclo[2.2.1]heptan-2-yl]phosphine |
| CAS No. | 74630-28-7 |
| Molecular Formula | C16H28ClP |
| Molecular Weight | 286.82 g/mol |
| Synonyms | Chloro(cyclohexyl)(1,7,7-trimethyl-2-norbornanyl)phosphine; (1R)-Chloro(cyclohexyl)[(1R,2S,5R)-1,7,7-trimethylbicyclo[2.2.1]hept-2-yl]phosphine; Camphor-derived cyclohexylchlorophosphine; (2-Bornyl)cyclohexylchlorophosphine; Cyclohexyl(2-bornyl)chlorophosphine; Phosphinous chloride, P-cyclohexyl-P-(1,7,7-trimethylbicyclo[2.2.1]hept-2-yl)- |
| EINECS | Contact for details |
Quality Control
Every batch of Chloro(Cyclohexyl)[1,7,7-Trimethylbicyclo[2.2.1]heptan-2-yl]phosphine is produced and tested under strict quality management protocols. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.
Storage
Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Keep away from heat, sparks, and open flames. Due to its sensitivity, minimize exposure to air and moisture during handling.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid or powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Melting Point | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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