Description

Dichloro[1,7,7-Trimethylbicyclo[2.2.1]heptan-2-yl]phosphine is a specialized organophosphorus compound featuring a camphor-derived, sterically hindered bicyclic framework. This unique structure makes it a valuable ligand precursor and building block in advanced chemical synthesis, particularly for creating tailored catalysts and functional materials. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing novel synthetic methodologies and high-value intermediates.

Application

• Catalyst Ligand Synthesis: Serves as a precursor for bulky, electron-donating phosphine ligands used in homogeneous catalysis, including cross-coupling and hydrogenation reactions.
• Pharmaceutical Intermediate: Employed in the research and development of complex active pharmaceutical ingredients (APIs) where its steric profile can influence stereoselectivity.
• Agrochemical Research: Used as a key synthon in creating novel pesticidal and herbicidal compounds with enhanced efficacy.
• Material Science: Acts as a functionalization agent or monomer in the synthesis of specialized polymers and advanced materials.
• Organometallic Chemistry: A crucial reagent for the preparation of transition metal complexes with unique reactivity profiles.
• Asymmetric Synthesis: Its chiral, rigid backbone makes it suitable for investigations into enantioselective catalytic processes.

Basic Information

Product Name	Dichloro[1,7,7-Trimethylbicyclo[2.2.1]heptan-2-yl]phosphine
CAS No.	74630-16-3
Molecular Formula	C10H17Cl2P
Molecular Weight	239.12 g/mol
Synonyms	2-Phosphabicyclo[2.2.1]heptane, 2-chloro-1,3,3-trimethyl-, 2-chloride; Dichloro(1,7,7-trimethyl-2-norbornanyl)phosphine; (1R,4R)-Dichloro(1,7,7-trimethylbicyclo[2.2.1]hept-2-yl)phosphine; Camphor-based phosphine chloride; 2-Norbornanylphosphonous dichloride, 1,7,7-trimethyl-; Dichloro(2-bornyl)phosphine
EINECS	Contact for details

Quality Control

Our Dichloro[1,7,7-Trimethylbicyclo[2.2.1]heptan-2-yl]phosphine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and titration methods, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your R&D and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (NMR)	≥ 97.0%
Chloride Content (Titration)	Conforms to theoretical
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.