Description

Hemoglobin Cowtown CAS NO 74623-09-9 is a specific, naturally occurring variant of hemoglobin, a vital oxygen-transporting protein found in red blood cells. This product is of significant interest for biochemical research and diagnostic applications due to its unique structural and functional properties. It is primarily utilized by researchers in biochemistry, hematology, and clinical diagnostics for studying hemoglobinopathies, developing analytical standards, and investigating oxygen-binding kinetics.

Application

• Biochemical Research: Used as a reference standard in studies of hemoglobin structure, function, and genetic variants.
• Clinical Diagnostics: Serves as a control material in laboratory tests for identifying and characterizing hemoglobin disorders such as thalassemias.
• Educational Purposes: Employed in academic and training settings to demonstrate principles of protein chemistry and molecular biology.
• Analytical Method Development: Utilized for calibrating instruments and validating analytical techniques like HPLC, electrophoresis, and mass spectrometry in clinical and research laboratories.
• Pharmaceutical Research: Potential use in foundational research for therapies targeting blood disorders and oxygen delivery.

Basic Information

Product Name	Hemoglobin Cowtown
CAS No.	74623-09-9
Molecular Formula	C2952H4664N812O832S40Fe4 (Hemoglobin tetramer, approximate)
Molecular Weight	~64,500 Da (for tetramer)
Synonyms	Hb Cowtown; Hemoglobin variant Cowtown; alpha2beta2(146HC3)His->Leu; HBB:c.442C>T; Hemoglobin ß-Chain Variant Cowtown; Deoxyhemoglobin Cowtown (reduced form); Oxyhemoglobin Cowtown (oxygenated form); Methemoglobin Cowtown (oxidized form)
EINECS	Contact for details

Quality Control

Our Hemoglobin Cowtown is produced and handled under stringent conditions to ensure batch-to-batch consistency and reliability for critical research applications. Each lot is characterized using advanced analytical techniques to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing specifications such as purity (by HPLC), spectral properties, and physical state is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized (freeze-dried) material at -20°C or below. Reconstituted solutions should be prepared with appropriate buffers and stored at 2-8°C for short-term use. This product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to prevent moisture uptake.

Specification

Item	Specification
Appearance	Lyophilized powder or solution
Identification (IR / UV-Vis)	Conforms to standard
Purity (HPLC)	≥ 95% (Hemoglobin Cowtown)
Assay (Spectrophotometric)	Contact for details
Iron Content	0.30 - 0.34% (as Fe)
Solubility	Soluble in water or appropriate buffer
Biological Activity (O2 binding)	Contact for details
Endotoxin Level	< 1.0 EU/mg (for research grade)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.