Description

Ceftriaxone Sodium CAS NO 74578-69-1 is a broad-spectrum third-generation cephalosporin antibiotic. It is a critical active pharmaceutical ingredient (API) valued for its efficacy against a wide range of Gram-positive and Gram-negative bacteria. This compound is essential for pharmaceutical manufacturers producing injectable antibiotic formulations for the treatment of serious infections.

Application

• Pharmaceutical API: Primary use as the active ingredient in sterile injectable antibiotic formulations.
• Hospital & Clinical Use: For the treatment of severe bacterial infections including meningitis, sepsis, pneumonia, and complicated urinary tract infections.
• Veterinary Medicine: Used in the formulation of antibiotics for treating bacterial infections in animals.
• Research & Development: Serves as a reference standard and key intermediate in pharmaceutical R&D for new antibiotic studies.
• Bulk Drug Manufacturing: Supplied to contract manufacturing organizations (CMOs) for large-scale production of finished dosage forms.

Basic Information

Product Name	Ceftriaxone Sodium
CAS No.	74578-69-1
Molecular Formula	C18H16N8Na2O7S3 · 3.5 H2O
Molecular Weight	661.59 g/mol (anhydrous basis)
Synonyms	Ceftriaxone Sodium Salt; (6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Sodium Salt; Rocephin (Brand Name); Cefatriaxone Sodium; Sodium Ceftriaxone; Antibiotic Ro 13-9904
EINECS	Contact for details

Quality Control

Our Ceftriaxone Sodium is manufactured under strict quality management systems. It is produced to meet or exceed the standards of major international pharmacopoeias, including USP (United States Pharmacopeia) and EP (European Pharmacopoeia). Every batch undergoes comprehensive analytical testing to ensure identity, purity, potency, and safety. A detailed Certificate of Analysis (COA) is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a low-humidity environment to prevent degradation. For long-term stability, consider storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to slightly yellowish crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	97.0% - 102.0% (on anhydrous basis)
pH (1% Solution)	6.0 - 8.0
Water Content (KF)	8.0% - 11.0%
Specific Optical Rotation	-165° to -180°
Heavy Metals	≤ 20 ppm
Residual Solvents	Meets USP/EP requirements
Bacterial Endotoxins	< 0.20 EU/mg
Sterility (if applicable)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.