Description

(2S,4S)-4-(Diphenylphosphino)-2-[(Diphenylphosphino)Methyl]-n-Phenyl-1-Pyrrolidinecarboxamide is a sophisticated chiral phosphine ligand of significant interest in advanced chemical synthesis. This compound matters for its ability to impart high enantioselectivity and catalytic efficiency in asymmetric transformations, a critical requirement for producing optically pure intermediates. It is primarily needed by research institutions and industrial R&D departments focused on pharmaceuticals, agrochemicals, and fine chemicals, where precise stereochemical control is paramount.

Application

• Asymmetric Catalysis: As a key chiral ligand in transition metal-catalyzed reactions such as hydrogenation, hydroformylation, and cross-coupling.
• Pharmaceutical Intermediate Synthesis: For the enantioselective production of active pharmaceutical ingredients (APIs) and complex drug candidates.
• Agrochemical Development: In the synthesis of chiral pesticides and herbicides where specific stereoisomers exhibit enhanced biological activity.
• Fine Chemical Manufacturing: Enabling the production of high-value, optically pure flavors, fragrances, and specialty materials.
• Academic & Industrial Research: Serving as a critical tool for methodology development in organic and organometallic chemistry.
• Catalyst Screening Libraries: As a component in high-throughput screening for discovering new catalytic systems.

Basic Information

Product Name	(2S,4S)-4-(Diphenylphosphino)-2-[(Diphenylphosphino)Methyl]-n-Phenyl-1-Pyrrolidinecarboxamide
CAS No.	74571-27-0
Molecular Formula	C41H37N2OP2
Molecular Weight	635.70 g/mol
Synonyms	(2S,4S)-(-)-2,4-Bis(diphenylphosphino)pentane-N-phenylcarboxamide; (S,S)-BDPP-N-Ph Carboxamide; (2S,4S)-BDPP-N-Phenylamide; (2S,4S)-4-(Diphenylphosphino)-2-[(diphenylphosphino)methyl]-N-phenylpyrrolidine-1-carboxamide; (S,S)-BDPP Carboxamide Derivative; Chiral Diphosphine Ligand 74571-27-0; P,P'-Bidentate Phosphine Ligand; SK-Phos Carboxamide Analog
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to confirm identity, chiral purity, and chemical purity. Certificates of Analysis (COA) detailing specific results for assay, enantiomeric excess, and impurity profiles are available upon request. We adhere to strict internal quality management protocols to ensure batch-to-batch consistency for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, the container should be purged with inert gas after each opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.