Description

5-(3-Trifluoromethyl-Phenoxymethyl)-Furan-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its furan-carboxylic acid core linked to a trifluoromethylphenoxy moiety. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly where enhanced metabolic stability and lipophilicity are desired. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in areas like kinase inhibitors or anti-inflammatory agents.
• Agrochemical Synthesis: Used in creating advanced herbicides or fungicides where the trifluoromethyl group can improve efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for designing novel ligands in catalytic systems or metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of specialty polymers or organic electronic materials requiring specific fluorine-containing aromatic units.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes to study biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied for bespoke organic synthesis projects at laboratory, pilot, and commercial scales.

Basic Information

Product Name	5-(3-Trifluoromethyl-Phenoxymethyl)-Furan-2-Carboxylic Acid
CAS No.	74556-59-5
Molecular Formula	C13H9F3O4
Molecular Weight	286.20 g/mol
Synonyms	2-Furancarboxylic acid, 5-[[[3-(trifluoromethyl)phenyl]oxy]methyl]-; 5-[(3-Trifluoromethylphenoxy)methyl]furan-2-carboxylic acid; 5-((3-(Trifluoromethyl)phenoxy)methyl)furan-2-carboxylic acid; Furan-2-carboxylic acid, 5-[(3-trifluoromethylphenoxy)methyl]-; 74556-59-5; 5-(3-Trifluoromethylphenoxymethyl)-2-furoic acid
EINECS	Contact for details

Quality Control

Our 5-(3-Trifluoromethyl-Phenoxymethyl)-Furan-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets exacting standards for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.