Description

1-Fluorohexestrol is a fluorinated synthetic estrogen derivative, structurally related to diethylstilbestrol. This compound is of significant interest in pharmaceutical research and development, particularly for its potential as a molecular probe or a synthetic intermediate. It serves the needs of research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in steroid chemistry, endocrine research, and the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of more complex fluorinated steroid analogs and potential therapeutic agents.
• Biochemical Research: Used as a reference standard or probe in studies investigating estrogen receptor (ER) binding affinity and structure-activity relationships (SAR).
• Endocrinology Studies: Employed in laboratory research to understand the effects of fluorinated estrogens on biological pathways.
• Fine Chemical Synthesis: A specialized intermediate for creating custom fluorinated compounds for advanced material science or agrochemical research.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	1-Fluorohexestrol
CAS No.	74536-79-1
Molecular Formula	C20H23FO2
Molecular Weight	314.40 g/mol
Synonyms	1-Fluorohexoestrol; 4,4'-(1,2-Diethyl-3-fluoropropane-1,3-diyl)diphenol; 1-Fluoro-1,2-diethyl-4,4'-dihydroxystilbene; 1-Fluoro-1,2-diethyl-4,4'-stilbenediol; Fluorohexestrol; NSC 112682; Hexestrol, 1-fluoro-
EINECS	Contact for details

Quality Control

Our 1-Fluorohexestrol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by spectroscopic methods (IR, NMR), and residual solvent analysis to ensure it meets high-purity research-grade standards. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.