Description

(6R)-7α-[(2-Benzofuranylacetyl)Amino]-3-Chloro-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid is a high-purity advanced pharmaceutical intermediate, specifically a cephalosporin derivative. This compound is critical for the research and development of next-generation β-lactam antibiotics, offering a sophisticated chemical scaffold for medicinal chemistry. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on antimicrobial drug discovery and synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel cephalosporin-class antibiotics.
• Antimicrobial Research: Used in biochemical research to study structure-activity relationships (SAR) and develop new antibacterial agents.
• Fine Chemical Synthesis: Serves as a precursor in multi-step organic syntheses for complex bioactive molecules.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Process Chemistry Development: Utilized in scaling up and optimizing synthetic routes for antibiotic production.

Basic Information

Product Name	(6R)-7α-[(2-Benzofuranylacetyl)Amino]-3-Chloro-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid
CAS No.	74512-71-3
Molecular Formula	C₁₇H₁₃ClN₂O₅S
Molecular Weight	392.81 g/mol
Synonyms	7β-[(2-Benzofuranylcarbonyl)amino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; 3-Chloro-7β-[(2-benzofuranylcarbonyl)amino]cephalosporanic acid; Cephalosporin derivative 74512-71-3; (6R,7R)-7-[(2-Benzofuranylcarbonyl)amino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; 3-Chloro-7β-(2-benzofurancarboxamido)cephalosporanic acid
EINECS	Contact for details

Quality Control

Our (6R)-7α-[(2-Benzofuranylacetyl)Amino]-3-Chloro-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.