Description

2-Bromo-2,2-Difluoro-1-Phenylethanol is a versatile fluorinated building block characterized by its bromine and difluoromethylene functional groups. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists for constructing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial synthon for the development of active pharmaceutical ingredients (APIs), especially those incorporating difluoromethylene ethers or other fluorine-containing motifs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the difluoro group can enhance biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or precursor for specialty polymers and advanced materials with unique surface properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic substitutions, and as a precursor for generating difluorocarbene or other reactive species in methodological studies.
• Liquid Crystal & OLED Material Development: Investigated for use in creating fluorine-containing components for electronic displays and organic light-emitting diodes.

Basic Information

Product Name	2-Bromo-2,2-Difluoro-1-Phenylethanol
CAS No.	74492-28-7
Molecular Formula	C8H7BrF2O
Molecular Weight	237.04 g/mol
Synonyms	α-Bromo-α,α-difluoro-β-hydroxyethylbenzene; 2-Bromo-2,2-difluoro-1-phenylethan-1-ol; 1-Phenylethanol, 2-bromo-2,2-difluoro-; Benzeneethanol, 2-bromo-2,2-difluoro-; (2-Bromo-2,2-difluoro-1-hydroxyethyl)benzene; 2,2-Difluoro-2-bromo-1-phenylethanol
EINECS	Contact for details

Quality Control

Our 2-Bromo-2,2-Difluoro-1-Phenylethanol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.