Description

Cefotetan Disodium is a second-generation, broad-spectrum cephalosporin antibiotic presented as its disodium salt. This compound is valued for its potent activity against a wide range of Gram-negative and anaerobic bacteria, making it a critical agent in clinical settings. It is primarily required by pharmaceutical manufacturers and research institutions for the formulation of injectable antibiotic preparations and advanced microbiological studies.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the manufacture of sterile injectable antibiotic formulations.
• Clinical Research: Used as a reference standard in studies investigating antibiotic efficacy, resistance patterns, and pharmacokinetics.
• Microbiological Media Preparation: Incorporated into selective culture media for laboratory identification of bacterial strains.
• Veterinary Medicine: Formulation of antibacterial treatments for veterinary use, following appropriate regulatory guidelines.
• Quality Control Laboratories: Serves as a high-purity analytical standard for HPLC, UV, and other pharmacopeial testing methods.

Basic Information

Product Name	Cefotetan Disodium
CAS No.	74356-00-6
Molecular Formula	C17H15N7Na2O8S4
Molecular Weight	663.57 g/mol
Synonyms	Cefotetan Disodium Salt; (6R,7S)-7-[[(4-(2-Amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl)carbonyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Disodium Salt; Apatef; Cefotan; Yamatetan; ICI 156834; 6,7-Dihydro-7-methoxy-8-oxo-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid 7-[(2-(2-Amino-4-thiazolyl)-4-carboxy-1,3-thiazetidin-1-yl)carbonyl] Disodium Salt
EINECS	Contact for details

Quality Control

Our Cefotetan Disodium is manufactured and tested to meet high-purity standards suitable for pharmaceutical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) that includes data for identity, purity, assay, and related substances. We adhere to cGMP (current Good Manufacturing Practice) guidelines to ensure consistency and traceability, supporting compliance with major pharmacopeias such as USP and EP.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to pale yellow powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	≥ 95.0%
pH (1% Solution)	4.5 - 6.5
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Bacterial Endotoxins	< 0.10 EU/mg
Sterility (for sterile grade)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.