Description

1-Ethynyl-4-Methoxy-2-Methylbenzene is a high-purity aromatic acetylene derivative, serving as a versatile and critical building block in advanced organic synthesis. Its unique molecular structure, featuring both an ethynyl and a methoxy group on a methyl-substituted benzene ring, makes it an essential precursor for constructing complex molecular architectures. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its reactivity to create new active molecules.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Organic Synthesis Building Block: Employed in Sonogashira coupling and other palladium-catalyzed reactions to introduce acetylene-functionalized aromatic systems.
• Chemical Research & Development: A valuable reagent for academic and industrial chemists exploring new synthetic methodologies and reaction pathways.

Basic Information

Product Name	1-Ethynyl-4-Methoxy-2-Methylbenzene
CAS No.	74331-69-4
Molecular Formula	C10H10O
Molecular Weight	146.19 g/mol
Synonyms	4-Methoxy-2-methylphenylacetylene; 2-Methyl-4-methoxyphenylacetylene; 1-Ethynyl-4-methoxy-2-methyl-benzene; 4-Methoxy-o-tolylacetylene; (4-Methoxy-2-methylphenyl)ethyne; 2-Methyl-4-(ethynyl)anisole
EINECS	Contact for details

Quality Control

Our 1-Ethynyl-4-Methoxy-2-Methylbenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining the product under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.