Description

(R)-(S)-Bppfa CAS NO 74311-56-1 is a specialized chiral ligand belonging to the bisphosphine class, known for its unique stereochemical configuration that enables precise control in asymmetric synthesis. This compound is critical for achieving high enantioselectivity in catalytic reactions, directly impacting the purity and efficacy of advanced pharmaceutical intermediates and fine chemicals. It is an essential reagent for research and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-performance catalysts for complex synthetic routes.

Application

• As a chiral ligand in asymmetric hydrogenation reactions for the production of enantiomerically pure pharmaceutical actives.
• Catalyst component in cross-coupling reactions (e.g., Suzuki, Heck) for constructing complex molecular architectures.
• Key reagent in the synthesis of optically active fine chemicals and natural product analogs.
• Used in academic and industrial R&D for developing new stereoselective catalytic processes.
• Potential application in the synthesis of advanced electronic materials and liquid crystals where chirality is a functional requirement.

Basic Information

Product Name	(R)-(S)-Bppfa
CAS No.	74311-56-1
Molecular Formula	C31H32P2•C4H4O4
Molecular Weight	Contact for details
Synonyms	(R)-(S)-1,1'-Bis[(S)-1-(diphenylphosphino)ethyl]ferrocene fumarate; (R)-(S)-BPPFA fumarate; (R)-(S)-1-[(S)-1',2-Bis(diphenylphosphino)ferrocenyl]ethyl methyl ether (common name variant); BPPFA; Josiphos ligand derivative; Chiral ferrocenylphosphine ligand; (R)-(S)-Bis[(S)-1-(diphenylphosphino)ethyl]ferrocene
EINECS	Contact for details

Quality Control

Our (R)-(S)-Bppfa is produced under strict quality management protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) due to its sensitivity to oxidation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Orange to red-brown powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.