Description

2'-Deoxyadenosine-5'-Triphosphate Disodium Salt is a high-purity nucleotide essential for enzymatic and biochemical research. This compound serves as a critical substrate for DNA polymerases, reverse transcriptases, and other enzymes involved in nucleic acid synthesis and sequencing. It is a fundamental reagent for molecular biologists, biochemists, and pharmaceutical researchers working in PCR, DNA sequencing, mutagenesis, and various diagnostic assay developments.

Application

• Molecular Biology Research: Essential substrate for PCR (Polymerase Chain Reaction), DNA sequencing, and site-directed mutagenesis.
• Enzymatic Assays: Used as a co-substrate in kinetic studies of DNA/RNA polymerases, kinases, and ATP-dependent enzymes.
• Diagnostic Kit Manufacturing: A key raw material in the production of kits for genetic testing, pathogen detection, and next-generation sequencing (NGS).
• Biochemical Synthesis: Employed in the enzymatic synthesis of oligonucleotides and modified nucleic acids.
• Cell Biology Studies: Used in research involving DNA repair mechanisms, apoptosis, and cell signaling pathways.
• Pharmaceutical Development: Serves as a reference standard and critical reagent in drug discovery targeting nucleic acid metabolism.

Basic Information

Item	Details
Product Name	2'-Deoxyadenosine-5'-Triphosphate Disodium Salt
CAS No.	74299-50-6
Molecular Formula	C10H14N5O12P3Na2
Molecular Weight	553.14 g/mol
Synonyms	dATP disodium salt; 2'-Deoxyadenosine 5'-triphosphate disodium; Deoxyadenosine triphosphate disodium salt; dATP-Na2; Adenosine, 2'-deoxy-, 5'-(tetrahydrogen triphosphate), disodium salt; 5'-dATP disodium; 2'-Deoxy-5'-ATP disodium salt
EINECS	Contact for details

Quality Control

Our 2'-Deoxyadenosine-5'-Triphosphate Disodium Salt is manufactured under strict quality systems to ensure batch-to-batch consistency and high performance in sensitive applications. Each lot is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profile, and bioburden are provided and available upon request, supporting compliance with research and diagnostic-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/UV)	Conforms
Purity (HPLC)	≥ 95%
pH (1% Solution)	6.0 - 7.5
Water Content (KF)	≤ 5.0 %
Endotoxin	< 10 EU/mg
Bioburden	To meet customer specification

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.