Description

trans-4-(5-Pentyl-1,3-Dioxan-2-Yl)Benzonitrile is a high-purity, specialized organic compound featuring a benzonitrile core linked to a pentyl-substituted dioxane ring. This compound matters as a critical advanced intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and advanced materials sectors. It is essential for research chemists and process development scientists working on liquid crystal materials, novel drug candidates, and other fine chemical applications requiring precise stereochemistry and functional group compatibility.

Application

• Liquid Crystal Synthesis: A key chiral intermediate for the development of ferroelectric and nematic liquid crystals used in advanced display technologies.
• Pharmaceutical Intermediates: Serves as a crucial building block in the multi-step synthesis of active pharmaceutical ingredients (APIs), especially those requiring a rigid, aromatic core with a protected diol functionality.
• Advanced Material Research: Used in the development of organic semiconductors, non-linear optical (NLO) materials, and other functional polymers.
• Chemical Synthesis & Catalysis: Employed as a specialized ligand or precursor in asymmetric catalysis and complex organic transformations.
• Agrochemical Intermediates: Potential use in the synthesis of novel, high-performance crop protection agents.
• Academic & Industrial R&D: A valuable reagent for methodological research in organic chemistry and material science laboratories worldwide.

Basic Information

Product Name	trans-4-(5-Pentyl-1,3-Dioxan-2-Yl)Benzonitrile
CAS No.	74240-66-7
Molecular Formula	C₁₆H₂₁NO₂
Molecular Weight	259.34 g/mol
Synonyms	4-[(2R,5S)-5-Pentyl-1,3-dioxan-2-yl]benzonitrile; (2R,5S)-2-(4-Cyanophenyl)-5-pentyl-1,3-dioxane; trans-2-(4-Cyanophenyl)-5-pentyl-1,3-dioxane; 4-(trans-5-Pentyl-1,3-dioxan-2-yl)benzonitrile; Benzonitrile, 4-[(2R,5S)-5-pentyl-1,3-dioxan-2-yl]-; LC Intermediate 74240-66-7; 5-Pentyl-2-(4-cyanophenyl)-1,3-dioxane (trans-)
EINECS	Contact for details

Quality Control

Our trans-4-(5-Pentyl-1,3-Dioxan-2-Yl)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and standard spectroscopic methods for identity confirmation, to ensure high chemical and isomeric purity suitable for demanding applications. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (trans-isomer)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.