Description

4-(Dichloromethyl)Benzonitrile is a versatile aromatic nitrile derivative featuring a reactive dichloromethyl substituent. This compound serves as a valuable high-purity chemical intermediate for the synthesis of more complex molecules in advanced research and manufacturing. It is primarily sought by pharmaceutical, agrochemical, and specialty chemical industries for constructing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring benzonitrile or benzyl halide motifs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, leveraging the reactivity of the dichloromethyl group.
• Ligand and Catalyst Precursor: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of novel polymers, liquid crystals, and organic electronic materials due to its aromatic core and functional handles.
• Custom Synthesis and R&D: A critical reagent for medicinal chemistry and process chemistry research in contract research organizations (CROs) and academic labs.

Basic Information

Product Name	4-(Dichloromethyl)Benzonitrile
CAS No.	74231-65-5
Molecular Formula	C8H5Cl2N
Molecular Weight	186.04 g/mol
Synonyms	p-(Dichloromethyl)benzonitrile; 4-(Dichloromethyl)benzenecarbonitrile; α,α-Dichloro-p-tolunitrile; 1-(Dichloromethyl)-4-cyanobenzene; Benzonitrile, 4-(dichloromethyl)-; p-Cyanobenzylidene chloride
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity. Our products undergo comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity and purity against stringent internal specifications. A Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.