Description

Cyclobutanecarbonitrile, 1-(4-Ethoxyphenyl)- (9Ci) is a specialized organic nitrile building block featuring a cyclobutane ring and an ethoxyphenyl substituent. This compound is valued for its unique steric and electronic properties, making it a critical intermediate in advanced synthetic chemistry. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders or metabolic diseases.
• Agrochemical Research: Serves as a versatile scaffold for developing new herbicides, fungicides, or plant growth regulators with enhanced efficacy and selectivity.
• Ligand & Catalyst Development: Used in organometallic chemistry to create novel ligands for catalysis, enabling more efficient and selective synthetic transformations.
• Material Science Precursor: Potential building block for advanced polymers or liquid crystals, where the rigid cyclobutane core can impart desirable thermal and mechanical properties.
• Chemical Biology Probe: Employed in medicinal chemistry to create tool compounds for investigating biological pathways and target validation.

Basic Information

Product Name	Cyclobutanecarbonitrile, 1-(4-Ethoxyphenyl)- (9Ci)
CAS No.	74205-20-2
Molecular Formula	C13H15NO
Molecular Weight	201.26 g/mol
Synonyms	1-(4-Ethoxyphenyl)cyclobutanecarbonitrile; 4-(1-Cyanocyclobutyl)phenetole; 1-(p-Ethoxyphenyl)cyclobutanecarbonitrile; Cyclobutanecarbonitrile, 1-(4-ethoxyphenyl)-; 74205-20-2; 1-(4-Ethoxyphenyl)cyclobutanenitrile; 4-(Cyclobutanecarbonitrile)phenetole
EINECS	Contact for details

Quality Control

Our Cyclobutanecarbonitrile, 1-(4-Ethoxyphenyl)- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.