Description

Cyclobutanecarbonitrile, 1-(3-Ethoxyphenyl)- (9Ci) is a specialized organic nitrile building block featuring a cyclobutane ring and an ethoxyphenyl substituent. This compound is valued for its unique structural framework, which makes it a versatile intermediate in advanced synthetic chemistry. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new herbicides and insecticides, where the cyclobutane moiety can impart favorable biological activity and metabolic stability.
• Ligand and Catalyst Development: The nitrile group can be transformed into various functional groups, making it useful for creating specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of monomers or additives for advanced polymers with specific thermal or optical properties.
• Chemical Biology Probes: Acts as a scaffold for developing molecular probes to study enzyme function and biological pathways.
• Custom Synthesis and Scale-up: Supplied for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects from milligram to kilogram scale.

Basic Information

Product Name	Cyclobutanecarbonitrile, 1-(3-Ethoxyphenyl)- (9Ci)
CAS No.	74205-16-6
Molecular Formula	C13H15NO
Molecular Weight	201.27 g/mol
Synonyms	1-(3-Ethoxyphenyl)cyclobutanecarbonitrile; 3-(1-Cyanocyclobutyl)phenetole; 1-(3-Ethoxyphenyl)cyclobutanenitrile; Cyclobutanecarbonitrile, 1-(3-ethoxyphenyl)-; Phenetole, 3-(1-cyanocyclobutyl)-; 74205-16-6; 1-(m-Ethoxyphenyl)cyclobutanecarbonitrile
EINECS	Contact for details

Quality Control

Our Cyclobutanecarbonitrile, 1-(3-Ethoxyphenyl)- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports research reproducibility and process development from discovery to pilot scale.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.