Description

Galactose, D-, [1-3H(N)] is a high-specific-activity, tritium-labeled derivative of the essential monosaccharide D-galactose. This radiolabeled compound is a critical tool for tracing and quantifying metabolic pathways, particularly in carbohydrate research and diagnostic development. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for advanced studies in metabolism, enzymology, and receptor binding assays.

Application

• Metabolic Pathway Tracing: Used as a radioactive tracer to study galactose metabolism, including the Leloir pathway, in cellular and in vivo systems.
• Enzyme Kinetics & Inhibition Studies: Essential for characterizing the activity of enzymes like galactokinase, galactose-1-phosphate uridylyltransferase, and other galactose-metabolizing enzymes.
• Receptor Binding Assays: Employed in research to investigate galactose-specific lectin binding and carbohydrate-protein interactions.
• Diagnostic Research: Serves as a key component in the development and validation of diagnostic tests for disorders such as galactosemia.
• Pharmacokinetic & Drug Metabolism Studies: Facilitates the tracking of drug candidates or prodrugs that utilize galactose moieties for targeted delivery or metabolism.
• Biochemical & Cell Biology Research: Applied in pulse-chase experiments and other techniques to monitor sugar uptake and utilization in various cell types.

Basic Information

Product Name	Galactose, D-, [1-3H(N)]
CAS No.	74182-37-9
Molecular Formula	C6H113HO6
Molecular Weight	~181.16 g/mol (unlabeled); Specific activity dependent.
Synonyms	D-[1-3H]Galactose; [1-3H]-D-Galactose; Tritiated D-Galactose; D-Galactose-1-t; Galactose (D-, tritiated); 1-Tritio-D-galactopyranose; 6-(Hydroxymethyl)-3,4,5-tris(hydroxy)oxane-2,3,4-triol-1-t
EINECS	Contact for details

Quality Control

Every batch of Galactose, D-, [1-3H(N)] is manufactured and analyzed under strict quality systems to ensure high radiochemical purity and specific activity. Quality assurance includes rigorous testing via HPLC and scintillation counting. A comprehensive Certificate of Analysis (COA) detailing specific activity, radiochemical purity, chemical purity, and solvent composition is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at or below -20°C in the original solvent as specified on the label. For long-term storage, keep at -70°C to -80°C. This product is light-sensitive (store away from light) and solutions should be handled with appropriate shielding and in designated radioactive work areas. Always adhere to local radiation safety regulations.

Specification

Item	Specification
Appearance	Clear, colorless solution
Specific Activity	5-30 Ci/mmol (Contact for exact value)
Radiochemical Purity	≥ 97% (by HPLC)
Chemical Purity	≥ 98% (by HPLC, UV detection)
Concentration	1 mCi/mL (in ethanol:water, 9:1 v/v or as specified)
Identification	Co-chromatography with reference standard

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.