Description

n-Benzoylphenylalanyl-Glycyl-Proline is a synthetic tripeptide derivative, specifically a benzoylated peptide, with the CAS registry number 74075-25-5. This compound serves as a crucial pharmaceutical intermediate and biochemical research tool, particularly in the study of enzyme inhibition and peptide-based drug discovery. It is primarily utilized by pharmaceutical R&D laboratories, biotech companies, and academic research institutions focused on protease-related pathways.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of more complex peptide-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or inhibitor in enzymatic assays, particularly for studying proteases like prolyl oligopeptidase (POP).
• Drug Discovery: Serves as a lead compound or scaffold for developing novel therapeutics targeting neurological disorders and inflammatory conditions.
• Academic Studies: Employed in university and institutional research to investigate peptide stability, metabolism, and structure-activity relationships (SAR).
• Reference Standard: Provides a high-purity standard for analytical method development and quality control in peptide manufacturing.

Basic Information

Product Name	n-Benzoylphenylalanyl-Glycyl-Proline
CAS No.	74075-25-5
Molecular Formula	C26H29N3O5
Molecular Weight	463.53 g/mol
Synonyms	Benzoyl-Phe-Gly-Pro-OH; Bz-Phe-Gly-Pro; N-Benzoyl-L-phenylalanylglycyl-L-proline; Z-Phe-Gly-Pro (Note: Z is sometimes used interchangeably with Bz for Benzoyl); Bz-F-G-P; N-(Benzoyl)-Phenylalanyl-Glycyl-Proline; Prolyl-Glycyl-N-Benzoylphenylalanine; (2S)-1-[(2S)-2-[[(2S)-2-Benzamido-3-phenylpropanoyl]amino]acetyl]pyrrolidine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our n-Benzoylphenylalanyl-Glycyl-Proline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and MS and NMR for structural confirmation, to ensure compliance with stringent research-grade specifications. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.