Description

Oxonorfloxacin is a synthetic fluoroquinolone derivative, a class of compounds renowned for their potent antibacterial activity. This high-purity intermediate is critical for the research and development of next-generation antimicrobial agents, offering a pathway to novel therapeutic solutions. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and antibiotic discovery.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel fluoroquinolone-based antibiotics.
• Antimicrobial Research: Used as a reference standard or active moiety in studies targeting bacterial DNA gyrase and topoisomerase IV.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to develop new antibacterial agents with improved efficacy and safety profiles.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for producing specialized chemical entities in a GMP or non-GMP environment.
• Analytical Standard: Utilized in quality control laboratories for method development, validation, and as a purity reference in HPLC or LC-MS analysis.

Basic Information

Product Name	Oxonorfloxacin
CAS No.	74011-42-0
Molecular Formula	C17H19FN4O4
Molecular Weight	362.36 g/mol
Synonyms	Oxonorfloxacin; 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid; Norfloxacin N-oxide; 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydroquinoline-3-carboxylic acid 1-oxide; AT-4140 N-oxide; AM-833 N-oxide; Lexinor N-oxide
EINECS	Contact for details

Quality Control

Our Oxonorfloxacin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and stringent control of related substances and residual solvents. A detailed Certificate of Analysis (COA) is provided with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.