Description

n-(Pivaloyl)Glycinohydroxamic Acid is a specialized hydroxamic acid derivative with the CAS registry number 73912-85-3. This compound is valued for its role as a potent and selective chelating agent and enzyme inhibitor, making it a critical intermediate in advanced research and development. It is primarily sought after by pharmaceutical researchers, agrochemical developers, and manufacturers of fine chemicals for applications in metalloenzyme inhibition and novel therapeutic agent synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting metalloproteases like histone deacetylases (HDACs).
• Biochemical Research: Used as a selective inhibitor in enzymatic studies to investigate the role of zinc-dependent and other metal-dependent enzymes.
• Agrochemical Development: Serves as a precursor in creating new generation herbicides and fungicides that act on specific plant enzyme pathways.
• Chemical Synthesis: Employed as a versatile chelating agent and protecting group in complex organic synthesis and peptide chemistry.
• Material Science: Investigated for use in creating specialized polymers and coatings with metal-binding properties.

Basic Information

Product Name	n-(Pivaloyl)Glycinohydroxamic Acid
CAS No.	73912-85-3
Molecular Formula	C7H14N2O3
Molecular Weight	174.20 g/mol
Synonyms	Pivaloyl Glycine Hydroxamic Acid; 2-[(2,2-Dimethylpropanoyl)amino]acetohydroxamic Acid; N-(2,2-Dimethylpropanoyl)glycinohydroxamic Acid; PGHA; N-Pivaloylglycine Hydroxamic Acid; N-(Pivaloyl)glycine Hydroxamic Acid; 73912-85-3; Glycine, N-(2,2-dimethyl-1-oxopropyl)-, 1-(hydroxyamide)
EINECS	Contact for details

Quality Control

Our n-(Pivaloyl)Glycinohydroxamic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.