Description

3-Epi-25-Hydroxyvitamin D3 is a key metabolite and stereoisomer of 25-hydroxyvitamin D3, playing a significant role in the study of vitamin D metabolism and signaling pathways. This compound is essential for research and development in the pharmaceutical and life sciences sectors, particularly for investigating the biological activity and metabolic fate of vitamin D analogs. It is primarily utilized by research institutions, pharmaceutical companies, and diagnostic manufacturers focused on endocrinology, bone health, and metabolic disorders.

Application

• Pharmaceutical Reference Standard: Serves as a critical certified reference material (CRM) for the quality control and assay development of vitamin D-based therapeutics and supplements.
• Biochemical Research: Used as a high-purity intermediate or analytical standard in studies of vitamin D metabolism, receptor binding, and enzymatic conversion pathways.
• Diagnostic Kit Development: Employed in the calibration and validation of immunoassays and LC-MS/MS methods for the precise quantification of vitamin D metabolites in clinical samples.
• Metabolite Profiling: Essential for distinguishing and quantifying the 3-epi isomer from 25-hydroxyvitamin D3 in complex biological matrices to understand its physiological relevance.
• Academic Research: A vital tool for universities and research labs exploring the structure-activity relationships and biological functions of vitamin D sterols.

Basic Information

Product Name	3-Epi-25-Hydroxyvitamin D3
CAS No.	73809-05-9
Molecular Formula	C₂₇H₄₄O₂
Molecular Weight	400.64 g/mol
Synonyms	3-Epi-25-Hydroxycholecalciferol; (23S)-25-Hydroxy-3-epi-vitamin D3; 3-Epi-Calcidiol; 25-Hydroxy-3-epi-vitamin D3; 3-Epi-25(OH)D3; 3-Epicalcidiol; 25-Hydroxy-3-epi-cholecalciferol; 3-Epi-25-Hydroxyvitamin D₃
EINECS	Contact for details

Quality Control

Our 3-Epi-25-Hydroxyvitamin D3 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. For long-term storage, keep the product desiccated to maintain stability. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.