Description

2,2-Difluoro-2-[4-(Trifluoromethyl)Phenyl]Acetic Acid is a high-value fluorinated aromatic building block essential for advanced organic synthesis. Its unique structure, featuring both difluoroacetic and trifluoromethylphenyl moieties, makes it a critical intermediate for introducing fluorine atoms into target molecules, thereby modulating their physicochemical properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides where fluorine substitution enhances bioactivity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated components in liquid crystal displays (LCDs), improving dielectric anisotropy and thermal stability.
• Polymer Science: Intermediate for creating specialty fluorinated monomers and polymers with enhanced chemical resistance, low surface energy, and improved weatherability.
• Organic Electronics: Used in the synthesis of fluorinated organic semiconductors and charge-transport materials for OLEDs and perovskite solar cells.
• Chemical Research: A versatile reagent in academic and industrial R&D for exploring new fluorination methodologies and creating complex molecular architectures.

Basic Information

Product Name	2,2-Difluoro-2-[4-(Trifluoromethyl)Phenyl]Acetic Acid
CAS No.	73790-11-1
Molecular Formula	C9H5F5O2
Molecular Weight	240.13 g/mol
Synonyms	α,α-Difluoro-4-(trifluoromethyl)phenylacetic Acid; 2,2-Difluoro-2-(4-trifluoromethylphenyl)acetic Acid; 4-(Trifluoromethyl)benzoylfluoride, difluoro-; [4-(Trifluoromethyl)phenyl]difluoroacetic Acid; Difluoro(4-trifluoromethylphenyl)acetic Acid; 73790-11-1; (4-Trifluoromethylphenyl)difluoroacetic Acid
EINECS	Contact for details

Quality Control

Every batch of 2,2-Difluoro-2-[4-(Trifluoromethyl)Phenyl]Acetic Acid is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard quality commitment includes comprehensive analysis via HPLC, NMR, and IR spectroscopy. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.