Description

Ethyl-2,2-Difluoro-2-(3,4-Difluorophenyl)Acetate is a high-value fluorinated organic intermediate, prized for its role in constructing complex molecules. Its core value lies in enabling the synthesis of advanced materials and active pharmaceutical ingredients (APIs) with enhanced properties. This compound is essential for R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate difluorinated aromatic motifs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, where the difluorophenyl group can improve metabolic stability and bioactivity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for creating fluorinated aromatic components used in electronic display technologies and organic semiconductors.
• Advanced Polymer Modification: Incorporated into specialty polymers to impart unique chemical resistance, thermal stability, or specific optical properties.
• Chemical Research & Development: A versatile reagent for academic and industrial research exploring new fluorination methodologies and organofluorine chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and fine chemical producers for use in multi-step synthesis projects under cGMP or ISO standards.

Basic Information

Product Name	Ethyl-2,2-Difluoro-2-(3,4-Difluorophenyl)Acetate
CAS No.	73789-95-4
Molecular Formula	C10H8F4O2
Molecular Weight	236.16 g/mol
Synonyms	Ethyl 2,2-Difluoro-2-(3,4-difluorophenyl)acetate; 2,2-Difluoro-2-(3,4-difluorophenyl)acetic Acid Ethyl Ester; Acetic acid, 2,2-difluoro-2-(3,4-difluorophenyl)-, ethyl ester; Ethyl α,α-Difluoro-3,4-difluorophenylacetate; 3,4-Difluoro-α,α-difluorobenzeneacetic Acid Ethyl Ester; (3,4-Difluorophenyl)difluoroacetic Acid Ethyl Ester; Ethyl (3,4-Difluorophenyl)difluoroacetate
EINECS	Contact for details

Quality Control

Our Ethyl-2,2-Difluoro-2-(3,4-Difluorophenyl)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided with every shipment. We support development and production needs with material suitable for research use through to cGMP-grade applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (by GC/HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.