Description

Metallothionein I CAS NO 73767-16-5 is a low-molecular-weight, cysteine-rich metal-binding protein crucial for intracellular metal homeostasis and detoxification. Its high affinity for essential and toxic heavy metals, particularly zinc, copper, and cadmium, makes it a vital biochemical tool for research and development. This protein is primarily utilized by researchers in biochemistry, molecular biology, and environmental toxicology to study metal metabolism, oxidative stress responses, and cellular protective mechanisms.

Application

• Biochemical Research: Used as a standard or reagent in studies of metal ion transport, sequestration, and detoxification pathways.
• Toxicology Studies: Employed to investigate cellular defense mechanisms against heavy metal toxicity (e.g., cadmium, mercury).
• Antioxidant Research: Applied in experiments exploring the role of metallothioneins in scavenging free radicals and mitigating oxidative stress.
• Diagnostic Development: Serves as a key component in developing assays and kits for detecting metal-binding proteins or related biomarkers.
• Pharmaceutical R&D: Investigated for potential therapeutic applications in conditions involving metal dysregulation or oxidative damage.
• Environmental Science: Used as a biomarker in ecotoxicology to assess exposure to metallic pollutants in biological systems.

Basic Information

Product Name	Metallothionein I
CAS No.	73767-16-5
Molecular Formula	Contact for details
Molecular Weight	~6-7 kDa (Approximate)
Synonyms	MT-I; Metallothionein-1; Metallothionein 1; MT1; Cadmium-Binding Protein; Zinc-Binding Protein; Copper-Binding Protein; Class I Metallothionein
EINECS	Contact for details

Quality Control

Our Metallothionein I is produced and handled under controlled conditions to ensure batch-to-batch consistency and reliability for research purposes. Each lot undergoes rigorous quality testing, including analysis for purity and identity. Certificates of Analysis (COA) detailing specific test results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture absorption. For short-term use, store at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to standard
Purity (HPLC)	≥ 95%
Protein Content (Biuret)	≥ 90%
Metal Content (AAS/ICP)	Zinc or Cadmium loaded forms available
Endotoxin Level (LAL)	< 1.0 EU/μg
Solubility	Soluble in aqueous buffers, dilute acids

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.