Description

Hemoglobin F Sardinia is a specific variant of fetal hemoglobin (HbF) characterized by a point mutation in the γ-globin chain. This high-purity biochemical is essential for advanced research into hemoglobinopathies and developmental biology. It serves as a critical reference standard and raw material for scientists and developers in the pharmaceutical, diagnostic, and life science research sectors.

Application

• Biochemical Research: Used as a purified standard in studies of hemoglobin structure, function, and oxygen-binding kinetics.
• Diagnostic Development: Serves as a key component in the calibration and validation of diagnostic assays for sickle cell disease and thalassemia.
• Therapeutic Research: Investigated in preclinical studies targeting hemoglobin switching for the treatment of β-hemoglobin disorders.
• Quality Control Reference: Employed as a certified reference material (CRM) in the quality control of related diagnostic kits and reagents.
• Hematology Studies: Utilized to understand the physiological role and stability of fetal hemoglobin variants under different conditions.

Basic Information

Product Name	Hemoglobin F Sardinia
CAS No.	73699-62-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	HbF Sardinia; Fetal Hemoglobin Sardinia; Hemoglobin F (Sardinia variant); γ-Globin Variant Sardinia; Hb F Sardegna; Fetal Hb Sardinia; Human Fetal Hemoglobin Sardinia
EINECS	Contact for details

Quality Control

Our Hemoglobin F Sardinia is produced and handled under strict quality protocols to ensure batch-to-batch consistency and purity for research applications. Each lot is accompanied by comprehensive analytical data. Certificates of Analysis (COA) detailing purity, identity, and relevant biological activity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	Lyophilized powder
Identification (HPLC/MS)	Conforms to standard
Purity (HPLC)	≥ 95%
Protein Content	≥ 90%
Solubility	Clear solution in suitable buffer
Endotoxin	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.