Description

1-Tosyl-3-Pyrrolidinone is a versatile and high-purity chemical intermediate featuring a pyrrolidinone core functionalized with a tosyl protecting group. This compound is valued for its role in facilitating complex organic syntheses, particularly in the development of advanced pharmaceutical compounds and specialized agrochemicals. It is an essential building block for research and production chemists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for complex molecule construction.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing nitrogen heterocycles.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides.
• Organic Synthesis Building Block: Serves as a protected precursor for introducing the 3-pyrrolidinone moiety into more complex molecular architectures.
• Research & Development (R&D): Employed in academic and industrial laboratories for method development and the exploration of new chemical entities.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals, dyes, and functional materials.

Basic Information

Product Name	1-Tosyl-3-Pyrrolidinone
CAS No.	73696-28-3
Molecular Formula	C11H13NO3S
Molecular Weight	239.29 g/mol
Synonyms	1-(4-Methylphenyl)sulfonyl-3-pyrrolidinone; 3-Pyrrolidinone, 1-(4-methylphenyl)sulfonyl-; 1-(Tosyl)-3-pyrrolidinone; N-Tosyl-3-pyrrolidinone; 1-Tosylpyrrolidin-3-one; 1-(p-Toluenesulfonyl)-3-pyrrolidinone; 1-(4-Methylbenzenesulfonyl)pyrrolidin-3-one
EINECS	Contact for details

Quality Control

Our 1-Tosyl-3-Pyrrolidinone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming the product meets agreed specifications. Our quality commitment supports applications requiring high standards, including cGMP-compliant pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.