Description

tert-Butyl 1-Amino-3-Methyl-1-Oxobutan-2-Ylcarbamate is a protected amino acid derivative, specifically a Boc-protected valine analog, serving as a crucial chiral building block in organic synthesis. This high-purity intermediate is essential for the production of complex molecules where stereochemical integrity and functional group compatibility are paramount. It is primarily utilized by pharmaceutical and biotechnology R&D teams for the synthesis of peptides, peptidomimetics, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, including protease inhibitors and other bioactive peptides.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate a protected valine residue, enabling the construction of complex peptide chains.
• Prodrug Development: Serves as a precursor for designing prodrugs where the tert-butoxycarbonyl (Boc) group provides stability and controlled release properties.
• Chemical Biology Research: Employed in the synthesis of labeled compounds, molecular probes, and tools for studying biological pathways and protein interactions.
• Agrochemical Synthesis: Acts as a building block for creating chiral active ingredients in crop protection products.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring high enantiomeric purity and reliable chemical performance.

Basic Information

Product Name	tert-Butyl 1-Amino-3-Methyl-1-Oxobutan-2-Ylcarbamate
CAS No.	73674-46-1
Molecular Formula	C10H20N2O3
Molecular Weight	216.28 g/mol
Synonyms	Boc-L-Valine; (S)-2-((tert-Butoxycarbonyl)amino)-3-methylbutanoic Acid; N-Boc-L-Valine; N-(tert-Butoxycarbonyl)-L-valine; Boc-Val-OH; (S)-2-(tert-Butoxycarbonylamino)-3-methylbutyric Acid; tert-Butyloxycarbonyl-L-valine; L-Valine, N-[(1,1-dimethylethoxy)carbonyl]-
EINECS	Contact for details

Quality Control

Our tert-Butyl 1-Amino-3-Methyl-1-Oxobutan-2-Ylcarbamate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, chiral analysis, and NMR, to ensure compliance with high-purity standards suitable for pharmaceutical research. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.5%
Enantiomeric Purity (Chiral HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.