Description

N,n-Dimethyl-2-Iodoacetamide is a versatile halogenated acetamide derivative, primarily valued as a key alkylating agent and building block in advanced organic synthesis. Its reactivity makes it essential for introducing functionalized acetamide groups into target molecules, enabling the development of novel compounds. This high-purity intermediate is particularly sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring functionalized acetamide motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Peptide Modification & Bioconjugation: Acts as an alkylating agent for modifying amino acid side chains (e.g., cysteine) in peptides and proteins for biochemical studies.
• Material Science Research: Employed in the creation of specialized polymers and functional materials where the iodoacetamide group can act as a reactive handle.
• Cross-linking Agent: Utilized in biochemical applications to create covalent cross-links between biomolecules.
• Chemical Biology Probes: A key reagent for developing activity-based probes and other tools for studying enzymatic function and protein interactions.

Basic Information

Product Name	N,n-Dimethyl-2-Iodoacetamide
CAS No.	73664-43-4
Molecular Formula	C4H8INO
Molecular Weight	213.02 g/mol
Synonyms	2-Iodo-N,N-dimethylacetamide; N,N-Dimethyliodoacetamide; Iodoacetic Acid Dimethylamide; Dimethylamino-2-iodoethanone; Acetamide, 2-iodo-N,N-dimethyl-; Iodoacetdimethylamide; (Dimethylcarbamoyl)methyl iodide
EINECS	Contact for details

Quality Control

Our N,n-Dimethyl-2-Iodoacetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.