Description

2',4'-Bis(Iodoacetylamino)Acetanilide is a specialized organic compound featuring two iodoacetyl functional groups, making it a valuable reagent for targeted chemical modifications. Its primary value lies in its ability to act as a potent alkylating agent, specifically reacting with thiol groups under controlled conditions. This property makes it essential for researchers and manufacturers in the pharmaceutical and life sciences sectors, particularly for the synthesis of active pharmaceutical ingredients (APIs), bioconjugation, and the development of biochemical probes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, especially those requiring targeted thiol-reactive modifications.
• Bioconjugation Reagent: Used for the site-specific labeling of proteins, peptides, and antibodies with fluorescent dyes, drugs, or other payloads via cysteine residues.
• Chemical Biology Research: Employed in the development of enzyme inhibitors, activity-based probes, and other tools for studying protein function and interaction.
• Crosslinking Agent: Facilitates the formation of covalent bonds between biomolecules for structural studies or the creation of stable complexes.
• Material Science: Potential use in the surface functionalization of polymers and nanomaterials to introduce specific reactive handles.

Basic Information

Product Name	2',4'-Bis(Iodoacetylamino)Acetanilide
CAS No.	73623-34-4
Molecular Formula	C₁₂H₁₂I₂N₂O₃
Molecular Weight	502.04 g/mol
Synonyms	N-(2-Acetamido-4-iodoacetamidophenyl)iodoacetamide; 2',4'-Di(iodoacetamido)acetanilide; N1-Acetyl-2,4-bis(iodoacetamido)benzene; 2,4-Bis[(iodoacetyl)amino]acetanilide; Acetanilide, 2',4'-bis(iodoacetylamino)-; N-(2-Acetamidophenyl)-2,4-bis(iodoacetamido)benzamide (related structure)
EINECS	Contact for details

Quality Control

Our 2',4'-Bis(Iodoacetylamino)Acetanilide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We can support development and production needs across research, pilot, and commercial scales with specifications tailored to your application requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.